MCD BIO CM156 Lecture Notes - Lecture 13: Human Genetics, Asthma, Old Age
23 Feb 2020
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Height is determined by a large number of genes with allele that increase or decrease height. Nutrition, childhood, ethnic diversity, very complex, or multi-factoral. Some diseases are more prevalent in other groups. Some disease happen later in life, so what happened: environmental influence. Obesity has increased over the past 20 years. Heart disease is similar to the numbers of obesity. Risk factors, like smoking, arthritis, high fat diet. Ex: heart disease occurs 10 years earlier in men than women. Twins, monozygotic shares more that diozygotic familial hypercol. He tried to explain complex inheritance through height. The more genes with more alleles, the more classes there are in variety until there is a normal distribution. Threshold for men and women on disease and other things. The proportion of phenotypic variation in a population that is due to genetics. Total variance of trait (vt ) = variance due to genetics (vg) + variance due to environment (ve )
