PSYCH 15 Lecture Notes - Lecture 10: Neuroplasticity, Ependyma, Neurogenesis

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17 Nov 2016
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10/27/16: lecture 10: development of the nervous system. Neural development--ongoing process (nervous system is plastic) Ectoderm (outermost)--patch of tissue on dorsal surface of embryo becomes neural plate. Mesoderm (middle)--sends chemical signals to induce development (the organizer ) Neural plate folds to form neural groove, fuses to form neural tube. Neural tube cells proliferate in specific ways: 3 swellings at the anterior end become forebrain, midbrain, and hindbrain. Proliferation is chemically guided by organizer areas (roof plate and floor plate) Posterior closure: spinal cord issues (spina bifida) Migrate from ventricular zone of neural tube. Migrating cells are immature (lack axons, dendrites) Somal--extension that leads migration develops, cell body follows. Glial-mediated migration (radial only)-- cell moves along glial network. Most cells engage in both types of migration. Structure dorsal to neural tube (formed from neural tube cells) After migration, cells align with others to form structures. May pay role in aggregation and other processes.

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