DIET 4475 Lecture Notes - Lecture 11: Vicia Faba, Glucose-6-Phosphate Dehydrogenase Deficiency, Galactosemia
Document Summary
Insufficient amounts of lactase (enzyme that digests the sugar lactose) Undigested lactose goes to the large intestine, draws in water, metabolized by bacteria producing acids and gas, resulting in cramps, abdominal distention, flatulence, and diarrhea. The enzyme activity of lactase declines with age, infection, and disease as well. Genetic disorder that results from compromised ability to metabolize the sugar galactose. Jaundice, vomiting, diarrhea, liver disease, ftt, sepsis can be fatal. Switch the baby from drinking breast milk or milk-based formula to a low galactose formula such as soy, or elemental. Adults: no organ meats or beans because they naturally have galactose. Enzyme needed to convert liver glycogen back to glucose also known as favism (after the fava bean) is an inborn error of metabolism. Mostly in males that predisposes to hemolysis (spontaneous destruction of red blood cells) and resultant jaundice in response to a number of triggers, such as certain foods, illness, or medication.
