MCB 2000 Lecture Notes - Lecture 16: Aldehyde Dehydrogenase, Alcohol Dehydrogenase, Aldehyde
10 Sep 2019
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Alcohol dehydrogenase: uses a coenzyme which becomes reduced oxidation reduction reaction, oh is becoming an aldehyde, the nad+ is accepting the electrons and one proton is free and becomes. Nadh: once you form aldehyde that"s going to be metabolized by aldehyde dehydrogenase also oxidation reduction, aldehyde is oxidized to carboxylic acid, nad+ reduced. Can metabolize it slowly, moderately, or you could metabolize it rapidly or you. Mutations in enzymes affect metabolism of enzymes don"t even metabolize it at all. Depending on the nature of the polymorphism effects on nature of enzymes . Ex: using caffeine (a drug has profound effects on the cardiovascular system) Some people can drink a lot of coffee and fall asleep like a baby at night whereas other people have one cup of coffee and are wired for an entire day. This has to do with the level of caffeine metabolism!
