MCB 2210 Lecture Notes - Lecture 11: Fluorescent Tag, Cell Adhesion, Zebrafish
17 Dec 2018
School
Department
Course
Professor
Document Summary
Cell dynamics applies to organelles, whole cells and cell communities; muscle cell precursors migrating and differentiating in vitro. Vsv-g movement in vesicles (transported on microtubules) from er to golgi to cell surface. Zebrafish lateral line organ is formed by coordinated deposition of rosette- forming cells from a migrating group. Cytoskeleton - group of several different types of filamentous protein fibers. Each type of cytoskeletal polymer consists of thousands of individual protein subunits that assemble into the polymer. Some structures are long-lived while others exist transiently. Can resist external forces and generate contractile forces. Polymers grow and shrink as subunits assemble and disassemble. And respond to its environment and different signaling inputs. Cell morphogenesis - size and shape changes. Cell organization - positioning and movement of organelles. Cell adhesion - contacting substrates and other cells. One of the most abundant proteins in eukaryotic cells (1-20% of total proteins) Sequence of actin has been highly conserved through evolution.
