MCB 2400 Lecture Notes - Lecture 4: Intron, Exonuclease, Gene Expression
5 Nov 2018
School
Department
Course
Professor
Document Summary
Transcription & mrna maturation phenotypic traits of organisms. Gene expression: decode information in genes to produce molecules that determine. Transcription: rna synthesis ssdna template, rntps, rna polymerase. Mrna specifies for a particular protein; 3 mrna bases in a row is a codon. Mrna sequence is complementary and antiparallel to dna template strand. It is the same as the coding strand; however, t is u. The enzyme used in transcription is rna polymerase ii. Promoter: recognition by rna pol ii is a prerequisite for transcription initiation. Sometimes rna polymerase transcribes past the termination site rat1 5"->3" exonuclease degrades extra rna. Gene is defined as the total dna sequence required to encode an mrna molecule. Not all dna contributes to the mrna and protein. Genes include coding and non-coding portions of dna. Introns: dna intervening between exons that does not encode polypeptide. Result of many outcomes from one gene. 5 methyl cap (added immediately during transcription)
