NURS 3110 Lecture 7: Lecture 7
Document Summary
Might find predominantly spores outside the body. Primarily disease of animals, humans rarely affected. Spores enter via injured skin or mucosa. Ex: imported goods inhalation: wool sorters (disease hemorrhagic pneumonia)and leather. Pulmonary - breathing organism in and getting infection. Necrotic ulcer - localized infection developed by tough (skin dying/black) Travels in the blood and engulfed by macrophages. Specimens: fluids, pus from lesions, sputum, blood. Mediastinal widening of lymph node = inflammation of lymph nodes. Treat with penicillin, tetracycline, ciprofloxacin - give early. Prevent by vaccinating, dispose of animal carcass properly. Gas hides, hair, bone products with eto to kill spores. 6 inoculations over 1. 5 years (5 different shots then need annual booster) Used for military personnel who are at high risk of exposure. Food poisoning (heat stable exotoxin) in rice, potato, meat. Spores survive short periods of cooking, reheating, germinate at room temp. Enterotoxin has weak pathogenicity in healthy individuals. Strict anaerobe (does not like o2 environment)
