PNB 2264 Lecture Notes - Lecture 10: Vasodilation, Loose Connective Tissue, Fibroblast

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Learning objectives: describe the structure and function of skin. Subcutaneous tissue: hypodermis, not technically part of the skin, protects the body. Dermis structure cells: the dermis contains blood vessels, free nerve endings, oil and sweat glands (which derive from epidermis but are located in dermis. Tissue layers: outer papillary layer, areolar c. t. ; forms dermal papillae (projections) to connect with overlying epidermis and supply blood via capillaries. Contains defense cells such as macrophages and mast cells in addition to fibroblasts (ct cells. : blood vessels, lymphatic vessels, nerve endings, sweat glands found. Inner reticular layer here: dense irregular c. t. Resists stretch in all directions: aka subcutaneous layer; superficial fascia, areolar connective tissue, in addition to fibroblasts, macrophages: ingest bacteria, etc. ; phagocytosis: mast cells: secrete histamine (inflammatory mediator, role in body"s defense (cid:498)first line(cid:499) to prevent bacteria and other pathogens from entering bloodstream.

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