Class Notes (1,100,000)
US (470,000)
UConn (8,000)
PNB (300)
Lecture 10

PNB 2264 Lecture Notes - Lecture 10: Vasodilation, Loose Connective Tissue, Fibroblast

Physiology and Neurobiology
Course Code
PNB 2264
Kristen Kimball

This preview shows half of the first page. to view the full 2 pages of the document.
Skin: Integumentary System
Learning Objectives
Describe the structure and function of skin
Structure of Skin
EPIDERMIS = Epithelial Tissue: stratified squamous keratinizing epithelium
to form a waterproof covering
o On top
o Epithelial tissue
Other cells include melanocytes (pigment melanin) and various immune and
sensory cells.
DERMIS = Connective Tissue
Largest organ in the human body
Subcutaneous Tissue
Not technically part of the skin
Protects the body
Epidermis Structure
Stratified Squamous Keratinizing Epithelium
o Multiple layers
o Protection not transport
o Flat
o Manufacture keratin: makes skin waterproof
Avascular: Like all epithelial structures, the epidermis has no blood vessels.
Five layers in thick skin
o Outermost layer = dead, keratinized cells
Layers of Epidermis
o Stratum Corneum: Outermost/most superficial layer; dead flat
keratin-filled cells.
Exposed to external environment
o Stratum Lucidum: Dead cells, anucleate (no organelles at all); seen in
thick skin
Far enough from the blood supply
o Stratum Granulosum: Granules (of keratin) visible in this layer;
process of kertinization begins here. Protein keratin forms filaments,
fills the cell
Still alive
o Stratum Spinosum: almost all are amitotic (cannot divide;) are living
cells connected by desmosomes.
o Stratum Basale: Regenerative layer; cells divide continuously.
Mitosing that is actively dividing cells, creating more epithelial
Dermis Structure
find more resources at
find more resources at
You're Reading a Preview

Unlock to view full version