PNB 2264 Lecture Notes - Lecture 11: University Of Manchester, Action Potential, Cytosol
16 Aug 2018
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Document Summary
Remember the properties of excitable cells and now apply them to muscle cells. Specific type of cell designed to generate movement: associated with bones (skeletal), organs and vessels (smooth muscle) and the heart (cardiac, stimulated to contract by movement of sodium and potassium across membrane. Movement: bones, tendons, muscle: via generation of tension. Contractibility: fibers shorten, generate force and pull on bones, tissues, vessels, pressure. Excitability: respond to stimulus, cns, hormones, physical. Do skeletal muscle push or pull or both: muscles only pull. They drive the movement of bones and tissues. Requires energy: conversion of atp into work. Structure dictates function; molecular to marco scale. It"s the (cid:373)eat you eat: hence striated muscle, muscle fibers, myoblasts, neuromuscular. Sarco prefix: sarcolemma muscle cell membrane, sarcoplasm cytosol, sarcoplasmic reticulum er. Fusion of individual muscle cells: multiple nuclei. Muscle fibers: 0. 1 to 4 cm length, 10 to 100 um in diameter connective tissue. External maina next to sarcolemma: reticular fibers.
