PNB 2264 Lecture Notes - Lecture 10: Sesamoid Bone, Hyaline Cartilage, Epiphysis

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Hematopoiesis - synthesis of blood cells in bone marrow. Blood vessels enter compact bone via volkmann"s canals. Calcium phosphate reacts with hydroxide to form crystals of hydroxyapatite. Communicates between central canals and other lacunae. No central canals are needed because blood capillaries are able to weave through the porous-like structure. Forms bones of the skull, scapula, etc. Elongation growth - as long as hyaline cartilage remains at the epiphyseal plate, the long bone is capable of increasing in length. Cartilage proliferation occurs on the epiphyseal side of the disk. Ossification occurs on the diaphyseal side of the disk. Appositional growth - add layers of compact bone. During early gestation/womb time, the fetal skeleton is formed of connective tissue membranes and hyaline cartilage. Build matrix, build collagen fibers, uptake calcium to mineralize/ossify bone. When calcium levels increases, osteoblasts uptakes calcium and stores it to decrease calcium levels. When calcium levels decreases, osteoclasts breaks downs bone to increase calcium levels.

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