PNB 2265 Lecture Notes - Lecture 11: Systemic Venous System, Lymph Node, Loose Connective Tissue

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Defense mechanisms of the body i: non-specific (innate immune) defenses v. specific (adaptive immune) defense mechanisms. Introduction: non-specific (innate immune) v. specific (adaptive immune) defense mechanisms. Analogy: bank walls (keep robbers out) vs. surveillance camera (to identify specific bank robber: role of immune (specific) responses, defend/protect against infection by microbes: viruses, bacteria, fungi, other parasites, immune surveillance. Body fluid homeostasis: organs (capsules) and tissues (less differentiated, less contained, returning filtered fluid back to vascular system. Ports of entry, breathing, take in food, urine out: examples: tonsils, peyer"s patches, and within lymph nodes (cortical area, no fibrous capsule, no afferent/efferent vessels (not well organized, gathering of lymphocytes. Recall: derivation of different blood cells from hemocytoblasts: myeloid stem cells, erythrocytes, leukocytes, all cell types except lymphocytes, lymphoid stem cells, lymphocytes, csf factors. Note you may encounter these terms: galt gut-associated lymphatic tissue (also called. Hemocytoblasts lymphoid stem cells b cells.

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