PNB 2265 Lecture Notes - Lecture 16: Intrapleural Pressure, Transpulmonary Pressure, Pulmonary Pleurae

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Ventilation: exchange of air between atmosphere and alveoli by bulk flow. Understand the forces that keep the lungs inflated. This diagram shows pulmonary pressures at rest (at the end of an unforced or tidal expiration. ) The transpulmonary pressure (keeping lungs open) exactly opposes the elastic recoil of the lungs, which is trying to collapse the lungs; and lung volume is stable. The lung volume at this time is the functional residual capacity. Note: the transpulmonary pressure (ptp) = force acting to inflate lung. Note that the volume of intrapleural fluid is greatly increased (for visual clarity. : purple = all alveoli, green = intrapleural space, outer green line = chest wall, tube = conducting pathways down respiratory pathways. *all pressures are given relative to atmospheric pressure (760 mmhg at sea level), and by convention; atmospheric pressure is denoted as 0 : pressures, atmospheric pressure (patm) = 0 (for convenience, alveolar pressure (palv)

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