PNB 2265 Lecture Notes - Lecture 24: Internal Anal Sphincter, External Anal Sphincter, Common Bile Duct

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Cck works on bulby part of pancreas: works at acinus. Secretin - works at duct: stimulus = low ph, increases ph. Composition: bile salts (cholesterol), bilirubin (rbc catabolism), lecithin, hco3- Cck (think fats, stimulates production of lipase) Release via gallbladder stimulated by cck and vagus. Temporary storage of wastes in rectum leads to stretching (mechanoreceptors activating) Parasympathetic output is decreased in rectum (internal anal sphincter) Regulation of water and ion (salt) balance. Osmotic gradient from the outer cortex to inner medulla. Orientation: afferent arteriole adjacent to distal tubule. Distal tubule comes back into contact with afferent arteriole. Glomerular capillaries (fenestrated capillaries - extra porous) Afferent arteriole comes in contact with distal tubule. There"s more here but she skipped slides. Bulk ow of protein-free plasma from glomerular capillaries into nephron. Back into blood (peritubular capillaries) - materials to be retained. Transport of materials into tubule for secretion.

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