PNB 2265 Lecture Notes - Lecture 6: Sex Steroid, Tetany, Thyroid
11 Sep 2017
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Protection: especially of vital organs (heart, lung) and brain. Allow movement / lever system: due to structure of joints (articulations) Storage depot for ca and p salts homeostasis of these electrolytes (especially ca++) is vital. Hemopoiesis: (cid:498)blood forming(cid:499) all blood cells develop in bone marrow. 1 marrow. children / infants; also found in other spaces within bone (including proximal epiphyses of humerus and femur in adults. : marrow cavity aka medullary cavity hollow diaphysis of long bone; filled with bone marrow. Red (active) erythropoiesis (blood formation) occurs here; found in marrow cavity of young. Bone is a dynamic (changing) tissue; constantly undergoing remodeling and turnover (breakdown/build up to keep strong) Responds to mechanical stress by strengthening; for example, weight training increases bone density. If blood supply is damaged, bone will die. Blood vessels enter compact bone via volkmann(cid:495)s canals run perpendicular to long axis. To central canal (haversian canal), blood vessels run parallel. Bone collagen encourages precipitation of hydroxyapatite salts (mineralizes)
