PSYC 2200 Lecture Notes - Lecture 11: Temporal Lobe, Acetylcholine, Frontal Lobe
3 Oct 2020
School
Department
Course
Professor
Document Summary
Acetylcholine (ach) involved in sympathetic/parasympathetic systems, motor systems, learning. Involved in motivation/effort, learning, fine movement; also emotion, reward pathways and drug addiciton. Primarily involved in modulating sympathetic and parasympathetic systems, also risk-taking (excitement. Primarily involved in emotion, temperature, sleep, sex, and appetite. Primary central inhibitory transmitter-- often used by inter-neurons (to modulate other pathways) Excitatory transmitter; primarily involved in learning and memory. Alcohol particularly affects frontal cortex (good/bad idea) and temporal lobe aspects of memory. Tolerance to ethanol (chronic use) results in up-regulation of nmda (sub-type of glutamate) receptors, so that abrupt withdrawal produces a hyperexcitable state with seizures, delerium tremens, and excitotoxic neuronal death. Rehab facilities have the ability to treat patients during withdrawal with sedatives, to offset the seizures until glutamate receptors down-regulate back to normal levels. When bodys natural opiates activate opiate receptors, the release of inhibitory neurotransmitters is shut down. Heroin mimics natural opiates and binds to opiate receptors, turning off dopamine inhibition.
