AS AM 100FF Lecture Notes - Lecture 1: Sexual Intercourse, Human Height, Population Genetics
Document Summary
Paper 1: heritability in the genomics era- concepts and misconceptions. In probability theory and statistics, variance i the expectation of the squared deviation of a random variable from its mean, and it informally measures how far a set of numbers are spread out from its mean. To partition the genetic sources of that variance. Partition out some factors by including them as covariates (height. Partition out some factors by including them as covariates (height can"t be explained by age and sex) Genotypic variation: crucial vocab (be particular in tests) At locus p32. 3, there are 100,000 basepairs of dna. A dna sequence that encodes a product with a distinct function. Gpx7 gene at locus 1 is a protein-coding gene. A particular form of a gene, e. g. a vs. a. For diploid individual, we can be aa (homozygous)/ aa (heterozygous)/ aa. Snp: single nucleotide polymorphism a. b. a variation in a single nucleotide that occurs at a specific position in the genome.