EEMB 40 Lecture Notes - Lecture 17: Aureus, Immunodeficiency, Vancomycin
2 Nov 2016
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Factors contributing to nosocomial infections in icu"s. About 25% of people have this bacteria harmlessly. This is why it is extremely widespread. Isn"t dangerous until the skin is broken and it causes an infection. It"s antibiotic resistant because it is so common. Study of 14,008 patients, 3,420 of them carriers of s. aureus. If you are a carrier, you are more likely to get a staph infection. The probability of death, if infected, was higher in non-carriers. 1980s-90s: resistance exceeds 80% in communities, 95% in most hospitals. Lactamase breaks a bond in the lactam ring of penicillin to disable the. Bacteria with this enzyme can resist the effects of penicillin and other molecule. It has evolved an ability to survive treatment with beta-lactam antibiotics, including penicillin, methicillin, and cephalosporins. Mrsa is often referred to in the press as a superbug. Vancomycin-resistant staphylococcus aureus (vrsa) is a strain of. Staphylococcus aureus that has become resistant to the glycopeptide antibiotic vancomycin.
