EEMB 40 Lecture Notes - Lecture 18: Herd Immunity, Dendritic Cell, Poliomyelitis Eradication
7 Nov 2016
School
Department
Course
Professor
Document Summary
Have to vaccinate a high number of the population to establish herd immunity. The measles vaccination was introduced into the us in 1963. The disease was declared eradicated by the cdc in 2000. The nation"s number of measles cases spiked to a total of 644 last year, far higher than the average of the previous year. Poorer countries can have a mortality rate of 10%. Vaccination rising: increased from 73% to 83% between 2000-2007 and remained constant ever since. Measles mainly persist in africa, india, pakistan because the vaccination rates are lower. Measles eradication will be very challenging but probably not as difficult to achieve as polio eradication. Infect macrophages (big eater) common wbc, abundant, generally will eat anything. Measles can infect macrophages when consumed by macrophages. Natural killer cell - kills your cells (infected cells. Innate immunity (rapid response): include macrophages and natural killer cells, dendritic cell. Adaptive immunity (slow response): only vertebrates have this part.
