BIPN 100 Lecture Notes - Lecture 2: Lipid Bilayer, Facilitated Diffusion, Endocytosis

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BIPN 100 Lecture 2
4/4/2018
Function of proteins in cell membranes ot’d
o Antigens
are membrane proteins that may allow for cellular identity
The cell will be recognized by the protein that is sticking out of the lipid
bilayer. The protein gives the identity, and usually will have other
functions
Transport
o Moving things in an out of cells
o Two ways
Bulk
Moving a lot of things that are generally bigger
Bulk is moving things across membranes, not through membranes
Endocytosis (into the cell) and exocytosis (out of the cell)
o Endocytosis has three types: phagocytosis (generally
bringing in big molecules; vacuole), pinocytosis (mainly
bringing in fluids and small molecules that are in the ECF;
vesicle), and receptor-mediated endocytosis (ligand binds
to a receptor for it to be engulfed by the cell)
Molecular
Through the cell membrane
Simple diffusion: lipid soluble that go right through
Protein-mediated transport: membrane proteins allow particles to
pass through the membrane (bigger or charged molecules)
o Facilitated diffusion: uses protein carriers in cell
membrane, molecules pass along the concentration
gradient; need a channel for the molecule to pass through;
no energy is used
o Active transport: ATP must be used; goes against the
concentration gradient; uses protein carriers in cell
pathways via channels;
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