BIMM 121 Lecture Notes - Lecture 12: Blue Cheese, Toothpick, Microorganism
26 Dec 2018
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Antibiotics: chemical compounds naturally produced by bacteria and fungi to act against other microorganisms: fleming discovered the first antibiotic, penicillin, by accident, penicillium colony grew on accident. Ring around the colony was inhibiting normal bacterial growth: formed from fruit mold and blue cheese (penicillium roquefortii) Antibiotics today: today, more than half of antibiotics are produced by strains of the genus streptomyces, bacillus, and others by. Penicillium (mold) and cephalosporium (mold): natural antibiotics: we obtain microbes capable of producing antibiotics and modify them for optimal use, antibiotic production. Measure diameters in mm (from edge of colony to edge. Scheme of microbe isolation and identification: patient analysis -> tests -> study microbe isolated from patient. Susceptibility to antimicrobials: methods to measure antibiotic susceptibility, kirby-bauer test, grow them on muller-hinton plates, plates made exactly the same, allowing consistency and ability to compare results, add antibiotic disks to plate, antibiotics will diffuse.
