COGS 1 Lecture Notes - Lecture 14: Royal Jelly, Synaptogenesis, Carbon Group
Document Summary
The study of changes in organisms caused by modification of gene expression rather than alteration of the genetic code itself. Non-cg methylation increases during 0-16 years, which coincides with synaptogenesis and pruning. Cg methylation starts at a high level and slowly decreases. Dna methylation is a process by which methyl groups are added to dna. When located in a gene promoter, dna methylation typically acts to repress gene transcription. Synaptogenesis is the formation of synapses between neurons in the nervous system. Although it occurs throughout a healthy person"s lifespan, an explosion of synapse formation occurs during early brain development, known as exuberant synaptogenesis. The vitamin folate is a key source of the one carbon group used to methylate dna. Some genes can be expressed from the inactive chromosome. It has been suggested that epigenetic processes occur during learning, stress and physical exercise. Studying catastrophes (dutch hongerwinter, great chinese famine, biafra famine in.
