PSYC 106 Lecture Notes - Lecture 23: Autonomic Nervous System, Sleep Deprivation, Learned Helplessness
Document Summary
Resistance to thinking about mood disorders as neurological disorders, but research shows they are highly heritable (large genetic contribution: to determine heritability, look at twin studies. Monozygotic twins (mz)- from same egg, genetically identical; concordance rate of. Mao inhibitors- prevent breakdown of neurotransmitters tricyclics and ssris- prevent reuptake of nt. Remission is greater than 50%, however relapse is common (is only temporarily) Prolonged and excessive ect can cause brain damage. Bipolar treatments: lithium- most effective at treating mania. Lithium is extremely effective and long lasting, but don"t know why. 5-ht transporter gene: have two different types of alleles for this gene (long or short, short allele is associated with more depression and suicidality. Rem onset, more rem periods, and more rapid eye movements during rem: one effective depression treatment is sleep deprivation (prevent from sleeping at all or from entering rem) long-lasting effects, and effect continues after stopping treatment too.
