PSYC 181 Lecture Notes - Lecture 15: Mptp, Designer Drug
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It just (cid:449)o(cid:374)(cid:859)t (cid:272)o(cid:373)e out right inside his body, there was a normal mind: took heroin recently. Usually affects those over 50, with symptoms coming up over the years. O(cid:374)e of the (cid:373)ost (cid:272)o(cid:373)(cid:373)o(cid:374) dege(cid:374)erate diseases of agi(cid:374)g, after alzhei(cid:373)er(cid:859)s. Slow, shuffling of feet loss of facial expression inability to blink spontaneously rigidity (jerking quality), tremoring, and stiffness. I(cid:374)(cid:272)e s(cid:455)(cid:373)pto(cid:373)s (cid:449)ere si(cid:373)ilar to parki(cid:374)so(cid:374)(cid:859)s disease, do(cid:272)tors ga(cid:448)e (cid:373)edi(cid:272)i(cid:374)e for. Parki(cid:374)so(cid:374)(cid:859)s disease, called l-dopa: miraculously worked on the drug addicts. L-dopa: medicine used to stop immobility in patients: replaces dopamine. If enough cells that (cid:373)ake dopa(cid:373)i(cid:374)e die, people get parki(cid:374)so(cid:374)(cid:859)s disease (tremors, rigidity, even complete immobility) I(cid:374) addi(cid:272)ts, pro(cid:272)ess of parki(cid:374)so(cid:374)(cid:859)s sped up (cid:1005)(cid:1004)(cid:1004) ti(cid:373)es. Mppp: s(cid:455)(cid:374)thesis of (cid:858)heroi(cid:374)(cid:859: however, (cid:449)as(cid:374)(cid:859)t (cid:272)areful e(cid:374)ough a(cid:374)d created mptp as well, which was deadly and could induce parkinsonism in primates, (cid:272)ie(cid:374)tists (cid:272)ould use this to resear(cid:272)h treat(cid:373)e(cid:374)ts for parki(cid:374)so(cid:374)(cid:859)s disease.
