PSYC 181 Lecture Notes - Lecture 16: Etiology, Exosphere, Maneb
Document Summary
Pa(cid:396)ki(cid:374)so(cid:374)"s disease: (cid:272)o(cid:373)(cid:373)o(cid:374), (cid:271)ut (cid:374)ot p(cid:396)e(cid:448)ale(cid:374)t since it hits later in life: classic symptoms: Tremor at rest: (cid:862)pill (cid:396)olli(cid:374)g(cid:863) (cid:449)he(cid:396)e it looks like you"(cid:396)e (cid:396)olli(cid:374)g a pill in your palm. A masklike facial appearance: blank face that lacks muscle tone: clinic characteristics: james parkinson 1817. Involuntary tremulous motion, lessened muscular power, in parts not in action and even when supported; with a propensity to bend the trunk forwards and to pass from a walking to a funning pace, the sense and the intellects uninjured. Intellects not totally uninjured, but for the most part, cognitive ability relatively spared. Severe (often untreatable) depression accompanies the disease, beyond the depression you get from having the neurodegenerative disease. Rigidity (cid:449)ith (cid:862)(cid:272)og-(cid:449)heel (cid:272)ha(cid:396)a(cid:272)te(cid:396)isti(cid:272)(cid:863): (cid:373)us(cid:272)les get stiff, a(cid:374)d you (cid:272)a(cid:374) (cid:271)e(cid:374)d thei(cid:396) limbs, making them look very ratchet. Aki(cid:374)esia: do(cid:374)"t (cid:373)o(cid:448)e a(cid:396)ou(cid:374)d: pathology of pa(cid:396)ki(cid:374)so(cid:374)"s. Death of dopamine neurons in the substantia nigra.
