ANFS241 Lecture Notes - Lecture 15: Endochondral Ossification, Hyaline Cartilage, Osteochondrosis
13 Dec 2019
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Document Summary
Conditions of the growing foal, rapid growth, overfeeding, mineral imbalances, genetic predisposition exercise/trauma. Toxicity: endochondral ossification, mesenchymal stem cells differentiate into chondrocytes, hyaline cartilage laid out as a template of the bone to be formed, matrix composed of type 2 collagen, soft, flexible, different centers of ossifications arise. Bone can grow and harden at the same time (this is good: physitis, most common, least worrisome, irregularity of growth plate, firm swelling, disappear after closure of growth plates. Temporary, goes away on its own: fast growth, high energy intake, osteochondrosis, defect in ossification, focal lesions form, necrosis of basal layer, osteochondrosis dissecans. Fetal malpositioning: not much to do here, that s the way the horse is, cervical vertebral malformation: wobbler disease, narrowing, compression of spinal cord. Trauma: clinical signs: 1-4 years, nutritional imbalance, rapid growth, more males than females, drugs to decrease nerve tissue swelling ix, ca:p ratio.
