BISC207 Lecture Notes - Lecture 11: Second Messenger System, Cell Membrane, Cyclic Guanosine Monophosphate

• School: University of Delaware
• Department: Biological Sciences
• Course: BISC207
• Professor: Van Golen Kenneth

Document Summary

What happens when you face a dangerous situation: fight or flight response. Adrenaline on body issues: non- essential parts shut down, airways relax, pupils dilate, heart rate speeds up, perspiration, adrenaline small protein, epinephrine made in adrenal gland. Cell signaling: complex system of communication that governs cellular activities, development, tissue repair, and immunity as well as homeostasis, i(cid:373)porta(cid:374)t for , neural transmission, tissue patterning, fight or flight, whe(cid:374) it goes wro(cid:374)g , tissue aberration, growth regulation. Types of receptors: cell surface less permeable ligands on outside, intracellular permeable ligands, no intracellular, tryptophan extracellular, atp extracellular, estrogen intracellular (steroids highly permeable, epinephrine extracellular, insulin extracellular. Nitric oxide (cyclic gmp: drives up blood pressure. Cell surface receptors: polar signaling molecule , extracellular domain ligand binding site , activates receptor change shape = activates, polar signaling molecules cannot cross the plasma membrane & rely on cell .