BISC207 Lecture Notes - Lecture 7: Hydrophile, Active Transport, Electron Microscope

• School: University of Delaware
• Department: Biological Sciences
• Course: BISC207
• Professor: Olabisi Oyenike

Document Summary

Protein structure is vital for its normal function. If the primary sequence is altered, all other levels of structure could be affected. Proteins can be integrated within the lipid bilayer. Plasma membranes contain as much protein as phospholipid. They can be amphipathic, since their side chains can be polar, charged, or non polar. Amphipathic proteins can integrate into lipid bilayers. They can fold into specific shapes based on their structure function. The fluid-mosaic model of membrane structure suggests. Some proteins are inserted into the lipid bilayer. Thus making the membrane a fluid, dynamic mosaic of phospholipids and proteins. Replaced the sandwich model, which proposed that the proteins were on either side of the bilayer. Biological sample that is thin sectioned and stained with heavy- metal dyes. Sye binds tightly to the polar head groups of phospholipids, but it does not bind well to the fatty acyl chains. Barrier to hydrophilic molecules and ions due to hydrophobic interior.