BISC300 Lecture Notes - Lecture 14: Transfer Rna, Allolactose, Trp Operon
27 Feb 2018
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8:44 pm: purple= things said in class, not on slides. Describe the levels at which cellular processes can be regulated. Describe/diagram the potential ways that transcription initiation can be controlled. Understand the importance of protein-dna interactions in the regulation of transcription. Describe/diagram how transcription of the operons encoding lactose utilization and tryptophan biosynthesis are regulated. Information flow/cellular processes can be regulated at multiple points. Dna (genes) 5"-3" -> rna (mrna) 5"-3" -> protein n-c. Cells have to decide where to invest their energy. Feedback loops - transcripts, proteins, and metabolites can go back and interact with mrna"s, proteins, and control what gets synthesized. Regulation is what"s in dashed lines - how cells make decisions about how to express genes in genomes. Very dynamic- can change in less than a minute. Changes what is transcribed so cells can adapt to environment. Prokaryotes have great flexibility for energy generation (metabolism)
