KAAP220 Lecture Notes - Primary Motor Cortex, Prefrontal Cortex, Phineas Gage

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Lecture 22
The Brain continued
Each sensory and motor region of the cerebral cortex is connected to an association area - region
that interprets the sensory data that comes in, puts meaning to it, and coordinates motor output
Visual cortex
Primary visual cortex - most posterior portion of occipital lobe; where all vision perceived from the
retina is directed
Visual association area - just anterior to primary visual cortex; interprets the visual information
coming into the primary visual cortex
Integrative centers of cerebral cortex
Areas that take information from association areas and then deliver to motor area
Primarily direct motor activities
Receive information from association areas, decide what to do with it, coordinate response, send it
to the motor area to make the response occur
Analytic functions
In areas of both hemispheres
But wernicke’s and Broca’s are in the left
Frontal eye field
In precentral gyrus
Controls learned eye movements; for example, scanning lines of text from the left top to right
and down the lines
Prefrontal cortex - in anterior portions of frontal lobes; integrates information from sensory
association areas; performs intellectual functions like planning, logic, reasoning, personality -
“where’s your filter?” The prefrontal cortex is your filter; notes what situation you’re in and
what the consequences of your actions may be; damage to prefrontal cortex typically results in
change of behavior and loss of self-control; functions in working memory
Phineas Gage
Broca’s area (motor speech area) - speech production; regulates breathing as we’re talking and
allow contraction of the muscles in the larynx and oral cavity to allow us to form and say words;
if this is damaged, you can make sounds but the skeletal muscle is no longer contracting to form
specific words; you know what you want to say and all you hear is moaning; know what they
want to say but they can’t say it
Wernicke’s area - language association and comprehension; receiving information from
somatosensory association areas and allows us to understand the meaning behind what others
and ourselves are saying; if damaged, you can form words but you don’t make sense; depends on
why/what other areas are damaged, sometimes they don’t know but sometimes they do know
what they want to say
Hemispheric lateralization - regional specialization of each hemisphere; even though it looks like
they’re both the same; specific functions happen only on the left or right
Left cerebral hemisphere - specialized language areas (like Broca’s and Wernicke’s); language-
based skills (like reading, writing, speaking); premotor cortex for hand movements is larger on
left side in right-handed people than in left-handed people; analytical tasks, such as math and
logic
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Document Summary

Transmits crude/general touch, not very specific; and pressure from the body, pain and temperature from the body too. First-order neuron from a receptor to the spinal cord; same posterior root; ascends into the posterior white columns of the spinal cord into the medulla where it synapses. Very similar in pathway just not crossing in the spinal cord; 1st order synapses on 2nd order in medulla where it crosses to the other side: spinocerebellar pathway. Proprioceptive information from muscle spindles, tendons, and joint capsules. 1st order neuron from a proprioceptor into the spinal cord, synapses on 2nd order neuron, which ascends up and goes to the cerebellum - some 2nd order neurons cross and some do not; all ascend to the cerebellum. Allows us to know where our bodies are in space and coordinate our movement based on that information: somatic motor pathways - descending pathways, always involve at least 2 motor neurons.

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