KAAP221 Lecture Notes - Lecture 3: Calcitriol, Extracellular Fluid, Adipose Tissue
Document Summary
Lecture 3: long-term regulation of growth, homeostatic regulation of growth. Requires cooperation of many endocrine organs, hormones involved are independently regulated, hormonal mixture alters metabolic operations, the combined effects of changing mixture produce unique growth patterns (we all grow in a different way) Insulin - allows glucose and amino acids across plasma membrane. Pth and calcitriol promote absorption of calcium salts for bone deposition. Calcitonin accelerates rate of bone deposition: primary hormones regulating growth. Androgens in males, estrogens in females have different target tissues. Alarm phase - immediate sympathetic response > epi and norepi; two main responses - energy reserves are mobilized (glucose), fight or flight response. Exhaustion phase - when energy reserves cannot be maintained, resistance phase ends; homeostatic regulation breaks down; organ systems begin to fail; mineral and electrolyte imbalances. Proteins leaving the blood causes fluid to follow, and causes edema; can happen in pregnant women. Edema makes diffusion difficult in the lungs if it"s pulmonary edema.