MEDT100 Lecture Notes - Lecture 1: Coombs Test, Bone Marrow Failure, Polycythemia
27 Sep 2017
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Iron deficiency: blood loss, deficiency of vitamin b12 or folic acid, bone marrow failure. Leukemia: abnormal wbc (low, bone marrow failure, presence of cytotoxic substance, disease of liver or spleen, radiation exposure. Leukemia: severe emotional or physical stress, tissue damage, coagulation, think pt, attp, monitoring drug dosages such as coumadin. Immunohematology: blood needed for surgery, emergency, anemia, newborns, labor and delivery, crossmatch, types and screen, direct antiglobulin test (dat), antibody identification, microbiology, sources of infection- virology, parasitology (parasite), mycology (molds and fungus), bacteriology, multiple specimen types, wound infections. Looking at the process from start to finish: statistical analysis of control material of known concentration, mean, sd, cv (coefficient of variation, non-statistical check procedures. Linearity checks: regent checks, temperature checks, calibration checks, total testing process, pre-analytical variables, transcription error, receive test order, patient identification/ preparation, specimen collection and transport, specimen separation and liquating, test utilization, analytical variables. In the lab: post analytical variables, approving test results, reporting results.
