NTDT200 Lecture Notes - Lecture 12: Fatty Liver, Abdominal Obesity, Central Nervous System
12 May 2016
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Making glucose: nervous system and red blood cells, amino acids yielding pyruvate, breakdown of body proteins. Creating an alternate fuel: use fat to fuel brain, ketone bodies. Protein tissue provides 90% of needed glucose during fasting. Fasting supports weight loss: because lean muscle shrinks: not best option for fat loss. Physical symptoms (wasting, slow heart rate and respiration, organ failure, impaired vision) Psychological symptoms (depression, anxiety and food related dreams) Metabolism similar to fasting: uses glycogen stores first, gluconeogenesis when glycogen is depleted, body tissues used somewhat even when protein provided in diet. Ketosis: is formed when glucose is lacking and fat break down is incomplete. Adverse side effects of low- carb, ketogenic diet: nausea. Fatigue (especially if physically active: constipation, low blood pressure, elevated uric acid (which may exacerbate kidney disease and cause inflammation of the joints in those predisposed to gout) Stale, foul taste in the mouth (bad breath)
