NTDT401 Lecture Notes - Lecture 6: Cytosol, Malonyl-Coa, Acetyl Group

• School: University of Delaware
• Department: Nutrition and Dietetics
• Course: NTDT401
• Professor: Fang Richard

Document Summary

**no deficiency; exists everywhere pantothenic acid= pantothenate (pantoic acid & beta alanine) Sh; sulfur in pantothenic acid hydrogen given away to reduce compounds and get acidic group to make it acetyl coa. Beta alanine + pantoic acid (peptide linkage)= pantothenate. **acyl carrier protein may use 4-phosphopantetheine as a coenzyme (fatty acid synthesis) 4 phosphopantetheine is not very movable; attached to enzyme in process of making fatty acids. Used to synthesize coa (needed for tca cycle; alpha ketoglutarate dehydrogenase reaction and fatty acid break down/synthesis and beta oxidation: coa; Synthesis requires pantothenic acid, cysteine and atp. Synthesis is inhibited by acetyl coa, malonyl coa and propionyl coa. Pantothenic acid essential for production of energy from. Need 9 coa to make 9 acetly coa. **body fat break down in cytosol if you use cho to make fat using acetyl coa have to go through glycolysis and tca cycle pyruvate dehydrogenase work in mitochondria.