BCH 3025 Lecture Notes - Lecture 6: N-Terminus, C-Terminus, Carboxylic Acid

• School: University of Florida
• Department: Biochemistry and Molecular Biology
• Course: BCH 3025
• Professor: Borum Peggy

Document Summary

Amino acids, peptides, and proteins- peptides and proteins. Chapter 3. 2: peptides- small condensation products of amino acids. Can be large: formation via condensation. A-amino group of one aa acts as a nuc to displace the hydroxyl group of another aa. Forms a peptide bond (substituted amide linkage) dipeptide. Hydroxyl group is a poor lg not readily displaces. At physiological ph, rxn here does not occur to any appreciable extent. Equilibrium tends to favor amino acid over the dipeptide: a polypeptide is smaller than a protein not the same thing. Peptide ends are not the same: numbering and naming starts from the amino terminus (aa residue at the end with a free a-amino group) The other end has a free carboxyl group carboxyl terminal (on the right) Will only have one carboxyl terminal and one amino terminal: an aa unit in a peptide is often called a residue .