BSC 2010 Lecture Notes - Lecture 4: Cell Nucleus, Pentose, Polynucleotide

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Nucleic acids are polymers specialized for storage, transmission, and use of genetic information. Nucleotide: pentose sugar + n-containing base + phosphate group. Bases: pyrimidines- single rings, purines- double rings. Sugars: dna contains deoxyribose, rna contains ribose. Nucleotides have 3 components: base (can be pyrimidines or purines, ribose or deoxyribose, phosphate. Nucleotides bond in condensation reactions to form phosphodiester linkages. Nucleic acids grow in the 5 to 3 direction. Oligonucleotides have about 20 monomers, and include small rna molecules important for dna replication and gene expression. Dna and rna are polynucleotides, the longest polymers in the living world. ***memorize table 3. 1 distinguishing rna from dna**: rna: Complementary base pairing: adenine and thymine, always pair (a-t, double bonded, cytosine and guanine, always pair (c-g) triple bonded. Base pairs are linked by hydrogen bonds. There are so many hydrogen bonds in dna and rna that they form a fairly strong attraction, but not as strong as covalent bonds.

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