BSC 4434 Lecture Notes - Lecture 1: Systems Biology, Bioinformatics, Genomics
19 Nov 2018
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Broad: use of computers to collect, analyze, and interpret biological information. Protein sequences that are derived from dna sequence genes. Set of software tools for molecular sequence analysis. Algorithm: recipe to implement something that is done by computers. Method: slide seq #2 along seq #1, count matches in all frames. For length of seq #1 compare letter at position 1 of seq #2 with position 1 of seq #1. Repeat for all letters of seq #2. Slide down compare letter at position 1 of seq #2 with position 2 od seq #1. Repeat for all letters of seq #1. Implement: write the computer code that will execute this algorithm in a specific language on a specific computer system. Use computer to gain novel biological knowledge. Anything that starts with a start codon, usually atg it can also be. Find a shine dalgarno sequence : sd ggagg (found upstream of this atg) Find that the sequence starts until the stop.
