MCB 4320C Lecture 6: Lecture 6
19 Jan 2019
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Document Summary
Appreciate how much of the human body is inhabited by bacteria. Establish a data analysis and coordinating center (dacc). Very few full genomes available in 2007. Began with pilot 16s rrna study to identify the most abundant organisms of the microbiome. Hmp sequenced 2,673 bacterial genomes of bacteria found on or in the human body. Today, this number is increasing very rapidly given the pacbio platform. Elucidate correlations between disease and the microbiome. little progress here for reasons to be described in a later lecture. Essentially, hmp has failed to appreciate the factors that can increase variability in human microbiome data. New technologies to assess microbiome were largely not developed by. Were mostly developed by the environmental microbiology field with several key computational biologists. hmp also slow to adopt new sequencing technologies. Establish a data analysis and coordinating center (dacc). dacc established to provide data, coordinate analyses and projects, develop metadata standards. Nice data catalog but redundant with ncbi.
