BIOL 1344 Lecture Notes - Lecture 15: Chronic Kidney Disease, Renal Vein, Kidney Stone Disease

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Lumbar region, on two sides of vertebral column. Left 2 cm higher than the right [due to liver] Lithotripsy: high frequency sounds used to break the stones. Chronic renal failure: kidneys filter out urea > urine. Every four minutes, entire system of blood is filtered. Aorta > renal artery > lobar artery >segmental artery >inter lobar artery . Kidney functions: get rid of nitrogenous waste products. Protein >amino acid deamination > -keto acid + nh3 [very toxic] > urea nh-co-nh2 [soluble, may be stored in bladder for some time] Gout: deposition of na-urate in joints painful. Creatinine cyclic compound > freely filtered in kidneys. Used to calculate golmerular filtration rate (gfr) Filtrate 125 ml/min = 180 liters/day [inulin used to calculate] Creatine > takes phosphate from atp > creatine phosphate. Excrete w/ urine through diuresis/ lack of adh. Aldosterone > na+ retention in kidneys >reabsorption in kidneys. Converting enzyme [ace in lungs] > angiotensin ii > vasoconstriction > bp rises.

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