BIOL 3332 Lecture Notes - Lecture 14: Rolling Circle Replication, Low Copy Number, Innate Immune System
17 Nov 2016
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Lecture 14: genetic resistance: hosts experience mutations. Some may make them less susceptible to infection. Adaptive immunity= antibodies: rna interference= amongst eukaryotes and archaea. Genome= total dna located in a cell: prokaryotes= have a single circular chromosome and a plasmid. Their division is not dependent upon the cell: divide through rolling circle replication. Make a new strand using the non- nicked strand as a template. New strand becomes a part of the plasmid. High copy number= many are present in cell. Low copy number= low number are present in the cell. Some can integrate into the bacterial chromosome. Can get genetic information through transformation, conjugation, transduction, transposition horizontal transmission. Regulon= controls multiple operons: ex: nitrogen regulon coordinates control of nitrogen metabolism. Gene operon regulon: transcriptome represented by the mrna, proteome represented by proteins, one gene hundreds of transcripts hundreds of proteins.
