BIOL 3305 Lecture Notes - Lecture 3: Start Codon, Stop Codon, Aminoacylation
Document Summary
(cid:120) genetic code: dna, three-letter code: triplet, rna, three-letter code: codon, a three letter code with 4 bases allows 64 combinations, more than enough for 20 amino acids, start codon and stop (codon). Redundancy in code, different codons, can give rise to insertion of same amino acid. The genomic code is degenerate, different codons can give rise to insertion of the same amino acid. To glu. (cid:198) acidic to acidic: different organisms show codon bias. (cid:131) refers to in different organisms, different codons are preferred, if a base is changed, can get a different amino acid, could be bad. Proteins stabilize these interactions. (cid:131) a g can form a hydrogen bond with a u, (wobble pairing or non- Standard) can be seen in crystal structures: inocine has capable of forming three hydrogen bonds with three different bases (refer to isoleucine; first two are standard then inocine can bind to.
