CHEM 312 Lecture Notes - Lecture 21: Migratory Insertion, Organometallic Chemistry, Leaving Group
17 Apr 2019
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Ligand substitution this substitution can be via the mechanism or associative or dissociative. Associative - this mechanism is like sn2 where the incoming ligand connects and associates with the metal before the leaving ligand leaves. The rate of the reaction occurs on how good the incoming ligand can associate with the metal center and how well the leaving group can leave. Dissociative - this mechanism is like sn1 where the leaving ligand leaves and leaves behind an open coordination site before the incoming ligand can coordinate with the metal. Rate = k1[lnml][l"]; use huge excess of incoming ligand l" to do pseudo first order reaction and obtain kobserved; redo at various l"s concentrations to get real k1. When a metal center has 14 or 16 electrons, the associative mechanism will dominate. Migration - migration is when an anionic ligand moves. Insertion - insertion is when a neutral ligand moves.
