MCB 150 Lecture Notes - Lecture 6: Endergonic Reaction, Hydrolysis
30 Jan 2017
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Document Summary
Brings protein back to its primary structure without breaking any peptide. Acids, bases, heat, and detergents (provides hydrophobic environment) can all. If denaturing agent is removed some proteins will regain structure and denature proteins properly fold. In vitro, in vivo has too many uncontrollable variables. Most reactions take a long time to occur, but cells need to carry out these. 2 broad categories of cellular reactions based on energy reactions in a second or less. Linking together of smaller molecules into large ones (dehydration reactions) of monomers to macromolecules. Breaking down molecules into smaller ones (hydrolysis). macromolecules monomers. Still requires energy (activation) to get it started. Bio: releases energy most of which is in the form of heat. Only speed things up, does not cause the reaction to occur. Need to bind to the active site usually just a few amino acids. Will likely cause the conformation (shape) of the substrate to change.
