MCB 150 Lecture Notes - Lecture 11: Intermembrane Space, Peptide, Cytosol

• School: University of Illinois
• Department: Molecular and Cell Biology
• Course: MCB 150
• Professor: Brad Mehrtens

Document Summary

Series of e- carriers in the inner mitochondrial membrane. Nadh pulls up and drops off e- Cristea allow for many e- chains to be present. Pumps protons from matrix to intermembrane space. Becomes oxidized when it gives e- to complex 3. Once e- are accepted it releases protons. Gets e- from complex 4 + protons to make water. Fadh2 drops its e- in complex 2. Gives up e- leaving protons in the matrix. Eubiconeom can take the e- to complex 3. Etc does not produce atp, just builds a gradient. Intermembrane is more positive relative to the matrix. Ph of the intermembrane is slightly more acidic (8) compared to matrix (7) Protons in the intermembrane space can go through porins to the cytosol to prevent acidity from getting out of hand. Atp synthase inorganic po4 together to form atp. When this happens, the protons do work which leads to atp.