MCB 150 Lecture Notes - Lecture 23: Phosphate, Sarcomere, Cell Division

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azurebutterfly65

7 Dec 2017

School

University of Illinois

Department

Molecular and Cell Biology

Course

MCB 150

Professor

B Mehrtens

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Document Summary

Cytoskeleton highly dynamic system of protein fibers of varying sizes: Reorganizes as cell responds to environment or divides. Provides physical support: important to animal cells with no cell wall. Allows for movement of cells and movement of material within an individual cell: Macrophages (type of wbc) need to be able to engulf material. Mitochondria are transported to areas that need atp. Cytoskeletal fibers three categories: (small diameter) Actin (or actin filaments, or actin microfilaments) Actin filaments monomers actin highly folded, globular proteins: G actin building block of actin filaments. Fairly moderate size: 375 amino acids, ~43 kda. Actin comprises 5 10% of all the protein in a cell. Actin monomers have tight binding sites for head-to-tail polymerization: To build the actin filament line up the + end and -end. Second actin rotates 166 to the first actin third actin rotates 166 relative to the first actin makes it look like a helical molecule .

Related Questions

The vesicles that transport materials from donor membranes to acceptor membranes include:

	1.	COP-II coated vesicles
	2.	COP-III coated vesicles
	3.	COP-I coated vesicles
	4.	Clathrin coated vesicles

2.5 points

QUESTION 11

During skeletal muscle contraction, the roles of ATP include:

	1.	ATP is not required for forming the crossbridges between myosin and actin filaments.
	2.	ATP is utilized as a structural linker to mediate the interaction between myosin and actin filaments
	3.	Hydrolysis of ATP provides energy for myosin head to move along actin filaments and the binding of ATP to myosin head allows the detachment of myosin fromactin filaments.
	4.	ATP binds to actin filaments to drive the power stroke of myosin head.

2.5 points

QUESTION 12

One of the functions of smooth endoplasmic reticulum is

	1.	Synthesizing steroid hormone in the endocrine cells of the gonad and adrenal cortex
	2.	Serves as the starting point of the biosynthetic pathway
	3.	Synthesizing secretory proteins
	4.	Degrading cell debris

2.5 points

QUESTION 13

The function of COP-II coated vesicles is mainly:

	1.	Transporting materials from endosomes to Golgi complex
	2.	Moving materials from the ER to the ERGIC and Golgi complex.
	3.	Transporting materials from Golgi complex back to endoplasmic reticulum.
	4.	Involved in receptor-mediated endocytosis.

2.5 points

QUESTION 14

Which of the following processes is completed in rough endoplasmic reticulum?

	1.	Chaperones help misfolded proteins fold correctly.
	2.	Proteins that target to nucleus are synthesized in rough endoplasmic reticulum.
	3.	O-linked glycosylation occurs in rough endoplasmic reticulum.
	4.	Misfolded proteins are destructed in rough endoplamic reticulum.

2.5 points

QUESTION 15

Kinesin is the motor protein that coorporates with microtubules. It has the following functions:

	1.	It uses GTP as energy source.
	2.	It can hydrolyze ATP and use the energy to drive cargo along microtubules from minus end to plus end.
	3.	It has a globular head that can act as GTPase
	4.	The tail of kinesin is more diverse and binds to cargo

2.5 points

QUESTION 16

For correct segregation and trafficking, lysosomal proteins are tagged in the cis-Golgi with phosphorylated mannose residues, and then the tagged lysosomal enzymes are recruited to clathrin coated vesicles by mannose 6-phosphate receptors.

True

False

2.5 points

QUESTION 17

The process that specialized cells, such macrophages, engulf relatively large particles is:

	1.	Called pinocytosis
	2.	Called phagocytosis
	3.	Mediated by COP-II coated vesicles
	4.	Called autophagy

2.5 points

QUESTION 18

Proteins synthesized on rough endoplasmic reticulum and smooth endoplasmic reticulum are imported co-translationally to their destinations

True

False

2.5 points

QUESTION 19

Treatment of cells with a drug that promotes microtubule disassembly disperses Golgi complex into separate stacks of membrane compartments, suggesting that:

	1.	Golgi complex is made of microtubules.
	2.	Microtubules are important for the organization of Golgi complex.
	3.	Microtubules are transported into Golgi complex
	4.	Golgi complex is composed of tubulin proteins

2.5 points

QUESTION 20

Which of the following is correct about signal sequence of a secretory protein?

	1.	It is an âaddress codesâ for protein trafficking pathways
	2.	It is usually located at the C-terminus.
	3.	It targets the ribosome and the protein that is being synthesized to endoplasmic reticulum.
	4.	It is removed in Golgi complex.

apricotgrasshopper117

i need help with this homwork please choose the correct answers and just be claer to read and understand for the slect the apply qusestions too and it is important i realy need the right answers so please be claer not write randomly i really need the correct answers to study for my test so hop you can help me

Question 1

What is the smallest cell you could find?

Question 2

TEMs appear as 3D images

True

False

Question 3

Bacteria are what cell type? Write one word as the answer in lowercase and using no syntax.

Flag this Question

Question 42 pts

ALL eukaryotic cells have which of the following. Click all that apply.

membrane enclosed cell organelles

mitochondria

Question 5

Prokaryotes and eukaryotes both have which if the following cellular components. Click all that apply.

Question 6

I am made of one 60s and one 40s subunit, which organelle am I?

protein

lipid

bacterial ribosome

Question 9

The difference between the rough and smooth ER is

the rough produces lipids where as the smooth does not

the rough has many folds and convolutions where as the smooth does not

the rough has ribosome embedded and the smooth does not

the rough is closer to the cell membrane whereas the smooth is closer to the nucleus

Question 10

The site where many lipids, including cell membrane is produced.

Question 11

Name the organelle: In muscle cells in particular, I would increase in number and size in response to frequent exercise

Question 12

In animal cells, glucose would be mobilized from its storage molecule (glycogen) in this part of the cell.

Question 13

Which of these is associated with the rough ER

production of carbohydrates

production of steroid hormones

production of ATP

production of proteins that are secreted from the cell

Question 14

Which organelle sorts, modifies and stores substances produced on the rough ER. Write two words as the answer in lower case separated by a space.

Question 15

Which organelle is responsible for ATP production. Write one word in the singular as the answer.

Question 16

You inherit all of your mitochondria from your

father

half from your mother and half from your father

your siblings

mother

Question 17

An organelle that contains chlorophyll

Question 18

Microtubules have a variety of roles, which of the options below is NOT one of them?

separate chromosomes

cilia and flagellum movement

tracks for organelle movement

constrict the cell during cell division

Question 19

Made of tubulin subunits

microfilaments

chromosomes

intermediate filaments

microtubules

Question 20

Name the part of the cytoskeleton that is made of two twisted rods of actin. Write one word as the answer in lower case.

Question 21

Which part of the cytoskeleton is made of the same protein as your hair and nails?

microfilaments

microtubules

Intermediate filaments

Question 22

The extracellular matrix is found outside of, but attached to the cell membrane?

True

False

Question 23

Which of the options below is an important function of the extra cellular matrix?

connecting cells together

regulate the movement of substances into and out of the cell

helping cells divide into two cells

keeping the cell in a fixed and ridged shape

Question 24

Which part of the cell wall has a high pectin content?

Question 25

Plants have mitochondria, chloroplasts, a cell wall, and nuclei.

True

False

Question 27

What accounts for 40% of the protein in our bodies?

Question 28

Animal cells have cell walls

True

false

MCB 150 Lecture Notes - Lecture 23: Phosphate, Sarcomere, Cell Division

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