BIOS 350 Lecture Notes - Lecture 1: Tuberculosis, Bone Fracture, Thymus
28 Sep 2016
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Document Summary
1. identification of unusual patterns trigger investigations and control efforts resource allocation evaluation of control and prevention efforts. 1. identify and confirm the problem cause of epidemic, predominant method of transmission. Define extent of involvement in terms of time, place and person. Supermarket, restaurants and bars meat products, cheeses, dressings, spices most infections 20-29 infection- uncontrolled growth of a microbe. Subclinical or inapparent infection- infection that never attains symptoms ( polio 1:300)- Contamination- body surfaces/inanimate objects carriage- salmonella, hep b, host- agent interaction. Physical characteristics- ability to survive in environment(fomites), bacteria more viable than virus(hep a virus) Endogenous infection(compound fracture)- organism doesn"t have to travel to host, it"s already present exogenous infection- organisms are transmitted to us. Host factors host defenses- nonspecific barriers, specific defenses(humoral vs cellular) humoral- derived from bone marrow, make antibodies (b cells) Cellular immunity- t cells( conductive role, t cells made in thymus).
