BIOLOGY 105 Lecture Notes - Lecture 2: Nutrient Density, Energy Density, Clinical Trial
Document Summary
Exposed two kinds of mice to two different diets while pregnant to determine if diet has a correlation to heart disease. Mice that were given standard mice diets + vitamin b12 had offspring that were healthy and had no issues with heart disease. Larger sample sizes are always better in experimental designs. Advantages: placebo effect may not apply to rodents, control every aspect of their diet, faster studies as life span is shorter, tests interventions that would be unethical on humans. Limitations: limited control over other factors, can"t claim causation. Advantages: large sample sizes, cheaper as there is no manipulation, results apply to humans because they came from humans, examines lot of factors. Limitations: expensive, sample sizes are usually smaller. Advantages: allow a differentiation between cause and effect, directly relatable to humans. Trust dietitians, peer-reviewed journals, sites ending in . gov or . edu or. High nutrient density: more nutrients in fewer calories.
