NURS 245 Lecture Notes - Lecture 1: Spasm, Atelectasis, Cardiac Output

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12 Apr 2016
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Note: there is no chronic pain condition where the degree of peripheral tissue damage alone accurately predicts the presence of severity of pain! Ischemia: psychological consequences: a. b. c. d. e. f. g. Transduction is the conversion of a stimulus (often mechanical, chemical, or thermal) into. 2-4 are very similar (if not the same!) in most types of pain transduction is where there are some differences between types of pain. Let"s take a second to review nociceptive vs. neuropathic pain -- K+, h+, serotonin, bradykinin, and histamine are released at the site of injury. Causes vasodilation in the localized area of trauma, leading to redness and swelling. Norepinephrine makes the area hypersensitive, meaning the action potential that triggers that stimulate the release of norepinephrine. the perception of pain occurs more easily. This process is also mediated by leukotrienes and prostaglandins. Efferent nerve fibers transmit action potentials that stimulate the release of norepinephrine.

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