BIOLOGY 151 Lecture Notes - Lecture 27: Tata Box, Binding Protein, Intron
Document Summary
Exam three is about the processes of gene expression. Regulated by transcription factor binding to regulatory region. Tata binding protein (tbp): binds tata box. Many other transcription factors bind and help rna polymerase ii localize to the transcription start site- 26bp from the tata box. Stem loop forms in rna as soon as it is transcribed while it is still in contract with. Rna polymerase causing rna polymerase to fall off the dna template. Bind to acceptor, branch and donor sites. Rna: the free 3" end of one exon attacks the 5" end of the other, the 3" and 5". Branch site attacks donor site, forming a loop. When cdki is expressed, but cdki rna binding protein is not, the splicing of the cdki mrna includes all three exons. Because the reading frame in exon 2 is very short, this mrna produces a smaller, non-functional cdki protein.