MICROBIO 140P Lecture Notes - Lecture 8: Bovine Spongiform Encephalopathy, Risus Sardonicus, Nictitating Membrane

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Bovine spongiform encephalopathy (bse: rising number of cases: 1986, peek: 1992-93. Cases have subsided but it still exists: first verified case: 1984, 1988: feed ban introduced. Offal: heads and brains of cows (the leftovers after slaughter) were used to feed the other cattle: 1991: sbo ban. Mad cow didn"t occur from nowhere: 1630s disease like mad cow was documented but in sheep. Mad cow: neurological disease that affects central nervous system. Brain develops lesions: holes: looks like swiss cheese. Scrapie: sheep and goats: bovine spongiform encephalopathy. Mad cow: cows: _______ spongiform encephalopathy. 1995 (11yrs after outbreak) stephen churchill, age 19, died of spongiform. Not the predictable very young and very old that are usually affected by sickness and disease) Infected cow tissue: cervical and terminal spinal cord, brain, retina, nictitating membrane (3rd eyelid) Carleton gajdusek: nobel prize in 70 or 80, in 1950 there was an outbreak in tribe in papua new guinea.

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