MICROBIO 140P Lecture Notes - Lecture 22: Antimalarial Medication, Antiprotozoal, Antibiotics
19 Apr 2016
School
Department
Course
Professor
Document Summary
Apothecaries would go out and find things in nature to make people feel better: imperial (observed) evidence. Materia medica: what, when, and how much to take of each medicine. Modern understanding of drugs: came from a better understanding of stains and dyes, cochineal (natural dye that comes from the cochineal scale insect that lives on cacti) Cranberry juice ( made with natural dyes ), red lipstick. Insects are crushed and used to make red dye: tyrian purple (comes from a mollusk, over time an understanding of the relationship between effective dyes and fabric developed. Helped to distinguish different types of cells. William henry perkin 1850 was asked by his mentor (hoffman) to synthesize quinine from cinchona tree bark (used against malaria) Grow quinine solely in the lab instead of extracting it from the bark. Mauveine 1856: perkin 1856 mauveine, hoffman 1869 synthetic dyes for staining cells.
